Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Family history of type 2 diabetes delays development of type 1 diabetes in TEDDY children with islet autoimmunity.

Diabetologia - 1 Mar 2026

Veijola Riitta, Tamura Roy N, Clasen Joanna L, Elding Larsson Helena, Warncke Katharina, Steck Andrea K, Haller Michael J, Jonsdottir Berglind, Akolkar Beena, Hagopian William A, Rewers Marian J, She Jin-Xiong, Ziegler Anette-Gabriele, Krischer Jeffrey P, Toppari Jorma

Abstract excerpt

AIMS/HYPOTHESIS: The aetiology of type 1 diabetes remains elusive. Family history of type 1 diabetes increases the disease risk but the role of other autoimmune diseases or type 2 diabetes in the family are unclear. Here, we aimed to analyse the effect of family history of diabetes and autoimmune diseases on development of islet autoimmunity and progression to type 1 diabetes. METHODS: The Environmental...

Topics

Join the communities discussing this publication.

Autoantibodies
Autoimmunity
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Disease Progression

Infant, Newborn

Islets of Langerhans

Source

Open in PubMed Open full text

Identifiers

PMID: 41359174
DOI: 10.1007/s00125-025-06613-1
PMCID: PMC12881113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Family history of type 2 diabetes delays development of type 1 diabetes in TEDDY children with islet autoimmunity.PMID 41359174Read ↗

Accelerated progression from islet autoimmunity to diabetes is causing the escalating incidence of type 1 diabetes in young children.Semantic proximity Read ↗

Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease.Semantic proximity Read ↗

IDDM1 and multiple family history of type 1 diabetes combine to identify neonates at high risk for type 1 diabetes.Semantic proximity Read ↗

Extended family history of type 1 diabetes in HLA-predisposed children with and without islet autoantibodies.Semantic proximity Read ↗

Association between family history, early growth and the risk of beta cell autoimmunity in children at risk for type 1 diabetes.Semantic proximity Read ↗

Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected FamiliesSemantic proximity Read ↗

Brief communication: early appearance of islet autoantibodies predicts childhood type 1 diabetes in offspring of diabetic parents.Semantic proximity Read ↗

Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY).Semantic proximity Read ↗

Predictors of the Initiation of Islet Autoimmunity and Progression to Multiple Autoantibodies and Clinical Diabetes: The TEDDY Study.Semantic proximity Read ↗

The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History on the Progression From Multiple Autoantibodies to Type 1 Diabetes: A TEDDY Study Report.Semantic proximity Read ↗

Characteristics of familial type 1 diabetes: effects of the relationship to the affected family member on phenotype and genotype at diagnosisSemantic proximity Read ↗

Family history of type 2 diabetes and characteristics of children with newly diagnosed type 1 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.