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Article

Interleukin-6 promoter polymorphism at position -174 in giant cell arteritis.

The Journal of rheumatology - 1 Nov 2005

Salvarani Carlo, Casali Bruno, Farnetti Enrico, Pipitone Nicolò, Nicoli Davide, Macchioni Pierluigi, Cimino Luca, Bajocchi Gianluigi, Catanoso Maria Grazia, Boiardi Luigi

Abstract excerpt

OBJECTIVE: To investigate potential associations between the -174 G/C interleukin-6 (IL-6) promoter polymorphism and susceptibility to and clinical features of giant cell arteritis (GCA), particularly in patients with or without polymyalgia rheumatica (PMR) and with or without ischemic complications. METHODS: One hundred and twenty-six patients with biopsy-proven GCA who were residents in Reggio Emilia, Italy,...

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Identifiers

PMID: 16265697

Genes

GCA

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Interleukin-6 promoter polymorphism at position -174 in giant cell arteritis.PMID 16265697Read ↗

IL-6 promoter polymorphism at position -174 modulates the phenotypic expression of polymyalgia rheumatica in biopsy-proven giant cell arteritis.Semantic proximity Read ↗

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