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Article

Association of CYP1A1, CYP1A2, GSTM1 and NAT2 gene polymorphisms with colorectal cancer and smoking.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000

Yoshida Kana, Osawa Kayo, Kasahara Mayumi, Miyaishi Aiko, Nakanishi Keiko, Hayamizu Saori, Osawa Yasunori, Tsutou Akimitsu, Tabuchi Yohiki, Shimada Etsuji, Tanaka Kenichi, Yamamoto Masahiro, Takahashi Juro

Abstract excerpt

We investigated CYP1A1*2A, CYP1A1*2C, CYP1A2*1C, CYP1A2*1F, GSTM1 and NAT2 gene polymorphisms, involving enzymes which metabolize many carcinogens, with reference to colorectal cancer risk. The distribution of these genotypes was not associated with risk overall. However, the CYP1A1*2A T/C genotype showed a significant association with colorectal cancer risk in never-smokers (odds ratio [OR], 3.06; 95% confidence...

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Identifiers

PMID: 18159984

Genes

NAT2
GSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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