Article
NAT2, GSTM-1, cigarette smoking, and risk of colon cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 1998
Slattery M L, Potter J D, Samowitz W, Bigler J, Caan B, Leppert M
Abstract excerpt
Cigarette smoking has been associated inconsistently with colon cancer. The extent to which genetic profile influences susceptibility to the inducement of colon cancer by cigarette smoking is not known. In this study, we evaluated the associations between smoking cigarettes and polymorphisms of t...
Topics
- Adult
- Aged
- Arylamine N-Acetyltransferase
- Case-Control Studies
- Colonic Neoplasms
- Confidence Intervals
- Female
- Gene Expression Regulation, Enzymologic
- Genotype
- Glutathione Transferase
- Humans
- Male
- Middle Aged
- Odds Ratio
- Polymorphism, Genetic
- Risk Factors
- Smoking