Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development.

Development (Cambridge, England) - 1 Nov 2004

Corrales JoMichelle D, Rocco Gina L, Blaess Sandra, Guo Qiuxia, Joyner Alexandra L

Abstract excerpt

The cerebellum consists of a highly organized set of folia that are largely generated postnatally during expansion of the granule cell precursor (GCP) pool. Since the secreted factor sonic hedgehog (Shh) is expressed in Purkinje cells and functions as a GCP mitogen in vitro, it is possible that Shh influences foliation during cerebellum development by regulating the position and/or size of lobes. We studied how...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Cerebellum
Share to Gene Dosage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hedgehog Proteins

Share to Kruppel-Like Transcription Factors

Share to Zinc Finger Protein GLI1

Share to Zinc Finger Protein Gli2

Share to Zinc Finger Protein Gli3

Source

Identifiers

PMID: 15496441
DOI: 10.1242/dev.01438

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development.PMID 15496441Read ↗

The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation.Semantic proximity Read ↗

Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development.Semantic proximity Read ↗

Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum.Semantic proximity Read ↗

The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum.Semantic proximity Read ↗

The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesisSemantic proximity Read ↗

Hedgehog Signaling in Cortical DevelopmentSemantic proximity Read ↗

Abnormal cerebellar development and Purkinje cell defects in Lgl1-Pax2 conditional knockout mice.Semantic proximity Read ↗

BMP signalling facilitates transit amplification in the developing chick and human cerebellumSemantic proximity Read ↗

MicroRNAs Promote Granule Cell Expansion in the Cerebellum Through Gli2.Semantic proximity Read ↗

Dual and Opposing Roles for the Kinesin-2 Motor, KIF17, in Hedgehog-dependent Cerebellar DevelopmentSemantic proximity Read ↗

Cerebellar proteoglycans regulate sonic hedgehog responses during development.Semantic proximity Read ↗

KIF3C Regulates Bergmann Glia Density and Patterning during Cerebellar DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.