Article

KIF3C Regulates Bergmann Glia Density and Patterning during Cerebellar Development

2024-12-02

Abstract excerpt

Kinesin-2 motors have been demonstrated to regulate Hedgehog (HH) signaling, particularly within the developing cerebellum (Spassky et al., 2008; Waas et al., 2024). KIF3A/KIF3B are required for ciliogenesis in mice, and loss of this motor complex results in cerebellar hypoplasia due to lack of mitogenic response of HH-responsive cerebellar granule neural progenitors (CGNPs). Homodimeric KIF17 regulates HH-depende...

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Literature Corpus work: a72d8301-ba6e-56c6-bb17-cbc338c37489
DOI: 10.1101/2024.12.02.626415

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