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Article

The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation.

Development (Cambridge, England) - 1 May 2006

Corrales JoMichelle D, Blaess Sandra, Mahoney Eamonn M, Joyner Alexandra L

Abstract excerpt

Foliation of the mouse cerebellum occurs primarily during the first 2 weeks after birth and is accompanied by tremendous proliferation of granule cell precursors (GCPs). We have previously shown that sonic hedgehog (Shh) signaling correlates spatially and temporally with fissure formation, and that Gli2 is the main activator driving Shh induced proliferation of embryonic GCPs. Here, we have tested whether the...

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Identifiers

PMID: 16571625
DOI: 10.1242/dev.02351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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