Article
<i>Apc<sup>Min</sup></i><sup>/+</sup> mouse model of colon cancer: Gene expression profiling in tumors
14 Oct 2004
Abstract excerpt
The Apc(Min/+) mouse is a popular animal model for studies of human colon cancer, but the molecular changes associated with neoplasia in this system have only been partially characterized. Our aim was to identify novel genes involved in tumorigenesis in this model. RNA from intestinal adenomas and from pre-neoplastic small intestine were prepared from six Apc(Min/+) mice. The tumor transcriptomes were analyzed...
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