Article
Functional form of Caveolin-1 is necessary for the assembly of alpha-hemolysin.
Biochemical and biophysical research communications - 19 Nov 2004
Vijayvargia Ravi, Suresh C G, Krishnasastry Musti V
Abstract excerpt
The assembly of alpha-HL was shown to rapidly progress upon its interaction with Caveolin-1. Treatment of A431 cells with alpha-HL has resulted in clustering of Caveolin-1 at cell-cell contacts. Consistent with this observation, alpha-HL mutants devoid of assembly property have not induced the clustering of Caveolin-1. While cholesterol depletion of A431 cells completely arrests the assembly of alpha-HL,...
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