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Article

Trans-SNARE pairing can precede a hemifusion intermediate in intracellular membrane fusion.

Nature - 21 Jul 2005

Reese Christoph, Heise Felix, Mayer Andreas

Abstract excerpt

The question concerning whether all membranes fuse according to the same mechanism has yet to be answered satisfactorily. During fusion of model membranes or viruses, membranes dock, the outer membrane leaflets mix (termed hemifusion), and finally the fusion pore opens and the contents mix. Viral fusion proteins consist of a membrane-disturbing 'fusion peptide' and a helical bundle that pin the membranes...

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Source

Identifiers

PMID: 15924133
DOI: 10.1038/nature03722

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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