Article
Evolution of the mannose-binding lectin gene in primates.
Genes and immunity - 1 Dec 2004
Verga Falzacappa M V, Segat L, Puppini B, Amoroso A, Crovella S
Abstract excerpt
The mannose-binding lectin MBL2 plays an important role in the innate immune system. It binds carbohydrates surface, acts as an opsonin and activates the complement system. With the aim of studying the evolution of the MBL2 gene in primates, we sequenced its coding region in 12 non-human primate species and compared them with the human sequence. We demonstrated that nucleotide and amino-acidic sequences of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
