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Article

The Drosophila metabotropic glutamate receptor DmGluRA regulates activity-dependent synaptic facilitation and fine synaptic morphology.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 13 Oct 2004

Bogdanik Laurent, Mohrmann Ralf, Ramaekers Ariane, Bockaert Joël, Grau Yves, Broadie Kendal, Parmentier Marie-Laure

Abstract excerpt

In vertebrates, several groups of metabotropic glutamate receptors (mGluRs) are known to modulate synaptic properties. In contrast, the Drosophila genome encodes a single functional mGluR (DmGluRA), an ortholog of vertebrate group II mGluRs, greatly expediting the functional characterization of mGluR-mediated signaling in the nervous system. We show here that DmGluRA is expressed at the glutamatergic...

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Identifiers

PMID: 15483129
DOI: 10.1523/JNEUROSCI.2724-04.2004
PMCID: PMC6730051

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