Article
Presynaptic impairment of synaptic transmission in Drosophila embryos lacking Gs(alpha).
The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Jul 2003
Hou Dongmei, Suzuki Kazuhiro, Wolfgang William J, Clay Catherine, Forte Michael, Kidokoro Yoshiaki
Abstract excerpt
Gs(alpha) is a subunit of the heterotrimeric G-protein complex, expressed ubiquitously in all types of cells, including neurons. Drosophila larvae, which have mutations in the Gs(alpha) gene, are lethargic, suggesting an impairment of neuronal functions. In this study, we examined synaptic transm...
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