Article
[ACT/AA polymorphism could duplicate the APOE*epsilon4-associated Alzheimer's disease risk].
Medicina clinica - 4 Sept 2004
Hernández-Charro Blanca, Moreno Sira, Valiente Alberto, Manubens José María, Villar María Dolores, Ramos-Arroyo María Antonia
Abstract excerpt
BACKGROUND AND OBJECTIVE: The association between the presence of the allele APOE*epsilon4 (apolipoprotein E) and sporadic Alzheimer disease (AD) has been long established. However, the possible influence of other genetic factors is still under debate. This study investigated the role of the a 1-antichymotrypsin (ACT) gene as a susceptibility factor for developing late-onset AD in the population of Navarra....
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