Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polygenic determinants of Alzheimer's disease: modulation of the risk by alpha-1-antichymotrypsin.

Annals of the New York Academy of Sciences - 16 Dec 1996

DeKosky S T, Aston C E, Kamboh M I

Abstract excerpt

The identification of apolipoprotein E (APOE) as a genetic risk factor modifying the chances of developing Alzheimer's disease (AD) has opened the possibility that other susceptibility genes exist that either independently modify the risk of developing AD or alter the risk imparted by APOE. We ha...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Apolipoproteins E

Share to Cohort Studies

Share to Gene Frequency

Share to Risk Factors

Source

Identifiers

PMID: 8993481
DOI: 10.1111/j.1749-6632.1996.tb32595.x

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8993481-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polygenic determinants of Alzheimer's disease: modulation of the risk by alpha-1-antichymotrypsin.PMID 8993481Read ↗

APOE*4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism.Semantic proximity Read ↗

No interaction between the APOE and the alpha-1-antichymotrypsin genes on risk for Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein E and alpha1-antichymotrypsin polymorphism in Alzheimer's disease.Semantic proximity Read ↗

Implication of alpha1-antichymotrypsin polymorphism in familial Alzheimer's disease.Semantic proximity Read ↗

alpha-1-Antichymotrypsin polymorphism in the gene promoter region affects survival and synapsis loss in Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein E and alpha-1-antichymotrypsin allele polymorphism in sporadic and familial Alzheimer's disease.Semantic proximity Read ↗

Alpha-1-antichymotrypsin gene polymorphism and risk for sporadic Alzheimer's disease in a German population.Semantic proximity Read ↗

Alpha1-antichymotrypsin polymorphism in Japanese cases of Alzheimer's disease.Semantic proximity Read ↗

Alpha 1-antichymotrypsin gene polymorphism and risk for Alzheimer's disease.Semantic proximity Read ↗

Alpha-antichymotrypsin gene polymorphism and risk for Alzheimer's disease in the Spanish population.Semantic proximity Read ↗

A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease.Semantic proximity Read ↗

Genetic variation in alpha(1)-antichymotrypsin and its association with Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.