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Article

Implication of alpha1-antichymotrypsin polymorphism in familial Alzheimer's disease.

Neuroscience letters - 13 Mar 1998

Nacmias B, Marcon G, Tedde A, Forleo P, Latorraca S, Piacentini S, Amaducci L, Sorbi S

Abstract excerpt

A common polymorphism in the alpha1-antichymotrypsin (ACT) gene has been shown to modify the Apolipoprotein E (ApoE) epsilon4-associated Alzheimer's disease (AD) risk identifying the combination of the ACT/AA and ApoE epsilon4/epsilon4 genotypes as a potential susceptibility marker for AD. Using the polymerase chain reaction, we analyzed the segregation of the ACT and ApoE polymorphisms in familial Alzheimer's...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9572591
DOI: 10.1016/s0304-3940(98)00134-7

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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