Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apolipoprotein E and alpha1-antichymotrypsin polymorphism in Alzheimer's disease.

Annals of neurology - 1 Oct 1996

Nacmias B, Tedde A, Latorraca S, Piacentini S, Bracco L, Amaducci L, Guarnieri B M, Petruzzi C, Ortenzi L, Sorbi S

Abstract excerpt

A recent observation has shown that a common polymorphism in the alpha1-antichymotrypsin (ACT) gene modifies the apolipoprotein E (ApoE) epsilon4-associated Alzheimer's disease (AD) risk identifying the combination of the ACT/AA and ApoE epsilon4/epsilon4 genotypes as a potential susceptibility marker for AD. We analyzed the segregation of the ApoE and ACT polymorphism in sporadic and familial AD patients. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Aged
Share to Alleles

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Apolipoproteins E

Share to Genotype

Share to Homozygote

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 8871590
DOI: 10.1002/ana.410400420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein E and alpha1-antichymotrypsin polymorphism in Alzheimer's disease.PMID 8871590Read ↗

No association between alpha1-antichymotrypsin polymorphism, apolipoprotein E and patients with late-onset Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein E and alpha-1-antichymotrypsin allele polymorphism in sporadic and familial Alzheimer's disease.Semantic proximity Read ↗

Implication of alpha1-antichymotrypsin polymorphism in familial Alzheimer's disease.Semantic proximity Read ↗

Alpha-antichymotrypsin gene polymorphism and risk for Alzheimer's disease in the Spanish population.Semantic proximity Read ↗

Alpha-1-antichymotrypsin gene polymorphism and risk for sporadic Alzheimer's disease in a German population.Semantic proximity Read ↗

[ACT/AA polymorphism could duplicate the APOE*epsilon4-associated Alzheimer's disease risk].Semantic proximity Read ↗

No association between the alpha 1-antichymotrypsin A allele and Alzheimer's disease.Semantic proximity Read ↗

Absence of association of alpha1-antichymotrypsin polymorphisms with Alzheimer's disease: a report on autopsy-confirmed cases.Semantic proximity Read ↗

No interaction between the APOE and the alpha-1-antichymotrypsin genes on risk for Alzheimer's disease.Semantic proximity Read ↗

Alpha1-antichymotrypsin polymorphism in Japanese cases of Alzheimer's disease.Semantic proximity Read ↗

No association between alpha-1-antichymotrypsin polymorphism and Alzheimer's disease in Chinese.Semantic proximity Read ↗

Polygenic determinants of Alzheimer's disease: modulation of the risk by alpha-1-antichymotrypsin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.