Article
No association between alpha1-antichymotrypsin polymorphism, apolipoprotein E and patients with late-onset Alzheimer's disease.
Neuroscience letters - 1 Aug 1997
Helisalmi S, Mannermaa A, Lehtovirta M, Ryynänen M, Riekkinen P, Soininen H
Abstract excerpt
Apolipoprotein E (APOE) has been identified as a major susceptibility marker for Alzheimer's disease (AD) and it has been proposed that a common polymorphism in the alpha1-antichymotrypsin (ACT) gene increases the risk of developing AD, when the combination of ACT/AA genotype and APOE epsilon4 al...
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