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Article

Nitric oxide synthase type 2 promoter polymorphisms, nitric oxide production, and disease severity in Tanzanian children with malaria.

The Journal of infectious diseases - 1 Dec 1999

Levesque M C, Hobbs M R, Anstey N M, Vaughn T N, Chancellor J A, Pole A, Perkins D J, Misukonis M A, Chanock S J, Granger D L, Weinberg J B

Abstract excerpt

Nitric oxide (NO) plays an important role in host resistance to infection with a variety of organisms. Two recent reports from Gabon and Gambia identified associations of malaria disease severity with the inducible NO synthase (NOS2) promoter G-954C and short allele (<11 repeats) pentanucleotide microsatellite polymorphisms, respectively. It was postulated that there would be a correlation of these polymorphisms...

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Source

Identifiers

PMID: 10558957
DOI: 10.1086/315140

Genes

NOS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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