Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma.

Gastroenterology - 1 Oct 2004

Merle Philippe, de la Monte Suzanne, Kim Miran, Herrmann Marc, Tanaka Shinji, Von Dem Bussche Annette, Kew Michael C, Trepo Christian, Wands Jack R

Abstract excerpt

BACKGROUND & AIMS: The molecular pathogenesis of human hepatocellular carcinoma (HCC) is understood poorly. In some tumors, activation of the Wnt/beta-catenin pathway as a result of beta-catenin gene mutations has been found. However, in many other HCCs, activation of the Wnt/beta-catenin pathway...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Carcinoma, Hepatocellular
Share to Cell Movement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytoskeletal Proteins

Share to Frizzled Receptors

Share to Liver Neoplasms

Share to Receptors, G-Protein-Coupled

Share to Trans-Activators

Source

Identifiers

PMID: 15480989
DOI: 10.1053/j.gastro.2004.07.009

Genes

FZD7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15480989-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma.PMID 15480989Read ↗

Wnt/Frizzled signaling in hepatocellular carcinoma.Semantic proximity Read ↗

Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells.Semantic proximity Read ↗

Wnt Signaling in Liver CancerSemantic proximity Read ↗

Frizzled 2‐induced epithelial‐mesenchymal transition correlates with vasculogenic mimicry, stemness, and Hippo signaling in hepatocellular carcinomaSemantic proximity Read ↗

Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinoma.Semantic proximity Read ↗

beta-Catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance.Semantic proximity Read ↗

Wnt signaling in hepatocellular carcinoma: analysis of mutation and expression of beta-catenin, T-cell factor-4 and glycogen synthase kinase 3-beta genes.Semantic proximity Read ↗

Alterations of Wnt/β-catenin signaling pathway in hepatocellular carcinomas associated with hepatitis C virus.Semantic proximity Read ↗

Overexpressed sFRP3 exerts an inhibitory effect on hepatocellular carcinoma via inactivation of the Wnt/β-catenin signaling pathway.Semantic proximity Read ↗

Mutations in the C-terminus of the X protein of hepatitis B virus regulate Wnt-5a expression in hepatoma Huh7 cells: cDNA microarray and proteomic analyses.Semantic proximity Read ↗

Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.Semantic proximity Read ↗

Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.