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Article

Wnt signaling in hepatocellular carcinoma: analysis of mutation and expression of beta-catenin, T-cell factor-4 and glycogen synthase kinase 3-beta genes.

Journal of gastroenterology and hepatology - 1 Mar 2003

Cui Jian, Zhou Xinda, Liu Yinkun, Tang Zhaoyou, Romeih Mahmoud

Abstract excerpt

BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) is a common killer cancer in the world. Recently, abnormal activation of the Wnt pathway has been found to be involved in the carcinogenesis of several human cancers including HCC. The goal of the present study was to investigate the mechanism of inappropriate activation of the Wnt pathway in hepatocarcinogenesis. METHODS: We analyzed the alterations of three...

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PMID: 12603528
DOI: 10.1046/j.1440-1746.2003.02973.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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