Article
Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinoma.
World journal of gastroenterology - 28 May 2015
Ding Shan-Long, Yang Zi-Wei, Wang Jie, Zhang Xiao-Lei, Chen Xiang-Mei, Lu Feng-Min
Abstract excerpt
AIM: To comprehensively understand the underlying molecular events accounting for aberrant Wnt signaling activation in hepatocellular carcinoma (HCC). METHODS: This study was retrospective. The HCC tissue specimens used in this research were obtained from patients who underwent liver surgery. The Catalogue of Somatic Mutations in Cancer (COSMIC) database was searched for the mutation statuses of CTNNB1, TP53, and...
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