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Article

Characterization of the renal phenotype in a mouse model of Marfan syndrome.

Virchows Archiv : an international journal of pathology - 1 Oct 2004

Hartner Andrea, Eifert Timo, Haas Christian S, Tuysuz Cigdem, Hilgers Karl F, Reinhardt Dieter P, Amann Kerstin

Abstract excerpt

The microfibrillar protein fibrillin-1 is expressed abundantly in the vasculature and the glomerulus of the kidney. Mutations in the fibrillin-1 gene lead to Marfan syndrome. The most common complication of this disease is aortic dilatation due to elastic deficiencies of the vascular wall. Severa...

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Source

Identifiers

PMID: 15480770
DOI: 10.1007/s00428-004-1081-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15480770-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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