Article
Deficiency in microfibril-associated glycoprotein-1 leads to complex phenotypes in multiple organ systems.
The Journal of biological chemistry - 12 Sept 2008
Weinbaum Justin S, Broekelmann Thomas J, Pierce Richard A, Werneck Claudio C, Segade Fernando, Craft Clarissa S, Knutsen Russell H, Mecham Robert P
Abstract excerpt
Microfibril-associated glycoprotein-1 (MAGP-1) is a small molecular weight component of the fibrillin-rich microfibril. Gene-targeted inactivation of MAGP-1 reveals a complex phenotype that includes increased body weight and size due to excess body fat, an altered wound healing response in bone a...
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