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Article

APOBEC3F Constitutes a Barrier to Successful Cross-Species Transmission of Simian Immunodeficiency Virus SIVsmm to Humans.

Journal of virology - 10 Aug 2021

Nchioua Rayhane, Kmiec Dorota, Gaba Amit, Stürzel Christina M, Follack Tyson, Patrick Stephen, Kirmaier Andrea, Johnson Welkin E, Hahn Beatrice H, Chelico Linda, Kirchhoff Frank

Abstract excerpt

Simian immunodeficiency virus infecting sooty mangabeys (SIVsmm) has been transmitted to humans on at least nine occasions, giving rise to human immunodeficiency virus type 2 (HIV-2) groups A to I. SIVsmm isolates replicate in human T cells and seem capable of overcoming major human restriction factors without adaptation. However, only groups A and B are responsible for the HIV-2 epidemic in sub-Saharan Africa,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Products, vif

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Share to Simian Acquired Immunodeficiency Syndrome

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Source

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Identifiers

PMID: 34132575
DOI: 10.1128/JVI.00808-21
PMCID: PMC8354236

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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APOBEC3F Constitutes a Barrier to Successful Cross-Species Transmission of Simian Immunodeficiency Virus SIVsmm to Humans.PMID 34132575Read ↗

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