Article

Species-specific differences in antagonism of APOBEC3 proteins by HIV-2 and SIVsmm Vif proteins

2020-09-08

Abstract excerpt

<h4>ABSTRACT</h4> SIVsmm infecting sooty mangabeys has been transmitted to humans on at least nine independent occasions, giving rise to HIV-2 groups A to I. SIVsmm isolates replicate in human T cells and seem capable of overcoming major human restriction factors without adaptation. However, only groups A and B are responsible for the HIV-2 epidemic in Sub-Saharan Africa and it is largely unclear whether adaptive...

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Literature Corpus work: 1ebe3a00-26cb-5b4c-9c72-ae2b69c07513
DOI: 10.1101/2020.09.08.287177

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