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Article

Coevolution of RANTES sensitivity and mode of CCR5 receptor use by human immunodeficiency virus type 1 of the R5 phenotype.

Journal of virology - 1 Nov 2004

Karlsson Ingrid, Antonsson Liselotte, Shi Yu, Oberg Monica, Karlsson Anders, Albert Jan, Olde Björn, Owman Christer, Jansson Marianne, Fenyö Eva Maria

Abstract excerpt

The evolution of human immunodeficiency virus type 1 (HIV-1) coreceptor use has been described as the acquisition of CXCR4 use linked to accelerated disease progression. However, CXCR4-using virus can be isolated only from approximately one-half of individuals with progressive HIV-1 disease. The other half continue to yield only CCR5-using viruses (R5 phenotype) throughout the course of disease. In the present...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15479822
DOI: 10.1128/JVI.78.21.11807-11815.2004
PMCID: PMC523262

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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