Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

How HIV changes its tropism: evolution and adaptation?

1 Dec 2008

Abstract excerpt

PURPOSE OF REVIEW: To present recent information on the evolution of coreceptor use from CCR5 alone to CCR5 and CXCR4, the impact CCR5 inhibitors have on this process, and new insights into HIV-1 binding to CD4 and CCR5. RECENT FINDINGS: The findings that are summarized include resistance to CCR5 inhibitors, genotypic predictors of coreceptor use, the link between coreceptor use and cell tropism, and new data on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV Research and Treatment
Share to vaccines and immunoinformatics approaches
Share to Virology and Viral Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19339951
DOI: 10.1097/coh.0b013e3283223d61

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

How HIV changes its tropism: evolution and adaptation?PMID 19339951Read ↗

Correlation of coreceptor usage and disease progressionSemantic proximity Read ↗

HIV-1 adaptation to low levels of CCR5 results in V3 and V2 loop changes that increase envelope pathogenicity, CCR5 affinity and decrease susceptibility to MaravirocSemantic proximity Read ↗

The CCR5 and CXCR4 coreceptors--central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection.Semantic proximity Read ↗

Evolution of coreceptor utilization to escape CCR5 antagonist therapy.Semantic proximity Read ↗

Evolution driven by a varying host environment selects for distinct HIV-1 entry phenotypes and other informative variantsSemantic proximity Read ↗

A pièce de resistance: how HIV-1 escapes small molecule CCR5 inhibitorsSemantic proximity Read ↗

Characterizing the Diverse Mutational Pathways Associated with R5-Tropic Maraviroc Resistance: HIV-1 That Uses the Drug-Bound CCR5 CoreceptorSemantic proximity Read ↗

HIV biological variability unveiled: frequent isolations and chimeric receptors reveal unprecedented variation of coreceptor use.Semantic proximity Read ↗

Coevolution of RANTES sensitivity and mode of CCR5 receptor use by human immunodeficiency virus type 1 of the R5 phenotype.Semantic proximity Read ↗

Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitro usage of alternative coreceptors during progressive HIV-1 subtype C infection.Semantic proximity Read ↗

Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease.Semantic proximity Read ↗

HIV-1 coreceptor tropism in India: increasing proportion of X4-tropism in subtype C strains over two decades.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.