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Article

Disruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis.

Endocrinology - 1 Mar 2012

Lee Seung-Jun, Lee Jennifer, Li Karen K, Holland Dianne, Maughan Heather, Guttman David S, Yusta Bernardo, Drucker Daniel J

Abstract excerpt

Exogenous glucagon-like peptide-2 receptor (GLP-2R) activation elicits proliferative and cytoprotective responses in the gastrointestinal mucosa and ameliorates experimental small and large bowel gut injury. Nevertheless, the essential physiological role(s) of the endogenous GLP-2R remain poorly understood. We studied the importance of the GLP-2R for gut growth, epithelial cell lineage allocation, the response to...

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Identifiers

PMID: 22253424
DOI: 10.1210/en.2011-1954
PMCID: PMC3606134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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