Article

Altered substance P signaling underlies perivascular sensory nerve dysfunction in inflammatory bowel disease

2020-05-02

Abstract excerpt

<h4>Objective</h4> Inflammatory Bowel Disease (IBD) is associated with cardiovascular disease risk and impaired intestinal blood flow, but the functional role of perivascular nerves that control vasomotor function of mesenteric arteries (MAs) perfusing the intestine is unknown in IBD. Because perivascular sensory nerves and their transmitters calcitonin gene-related peptide (CGRP) and substance P (SP) are importa...

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Literature Corpus work: 92aa4a08-4f20-59a7-9e4c-dca36b6de5f0
DOI: 10.1101/2020.04.29.066126

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