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Article

Evidence for codon bias selection at the pre-mRNA level in eukaryotes.

Trends in genetics : TIG - 1 Nov 2004

Willie Erik, Majewski Jacek

Abstract excerpt

We investigated codon usage patterns across eukaryotic exons. We have shown that in humans codon preference varies with distance from the splice sites. This is consistent with the distribution of RNA elements involved in splicing regulation. Our results provide the first evidence that selection at the pre-mRNA level influences codon usage in humans. We also show that systematic trends in codon usage are found in...

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PMID: 15475111
DOI: 10.1016/j.tig.2004.08.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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