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Article

DNA binding domain in the replication checkpoint protein Mrc1 of Schizosaccharomyces pombe.

The Journal of biological chemistry - 17 Dec 2004

Zhao Hui, Russell Paul

Abstract excerpt

The replication checkpoint is activated when replication forks are obstructed by DNA lesions or protein complexes bound to DNA or when DNA synthesis is restrained by the limited availability of deoxyribonucleotides. This checkpoint preserves genome integrity by stabilizing stalled forks and delaying the onset of mitosis. In the fission yeast Schizosaccharomyces pombe, Mrc1 is a replication checkpoint adaptor...

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Identifiers

PMID: 15471884
DOI: 10.1074/jbc.M410449200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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DNA binding domain in the replication checkpoint protein Mrc1 of Schizosaccharomyces pombe.PMID 15471884Read ↗

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