Article
alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor.
Journal of cell science - 15 Oct 2004
Muramatsu Hisako, Zou Peng, Suzuki Hiromichi, Oda Yoshihiro, Chen Guo-Yun, Sakaguchi Nahoko, Sakuma Sadatoshi, Maeda Nobuaki, Noda Masaharu, Takada Yoshikazu, Muramatsu Takashi
Abstract excerpt
Midkine is a heparin-binding growth factor that promotes the growth, survival, migration and differentiation of various target cells. So far, receptor-type protein tyrosine phosphatase zeta, low-density-lipoprotein-receptor-related protein and anaplastic lymphoma kinase have been identified as receptors for midkine. We found beta1 integrin in midkine-binding proteins from 13-day-old mouse embryos. beta1-Integrin...
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