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Integrin signaling in skeletal development and function

1 Mar 2014

Abstract excerpt

Integrins are cell surface receptors that connect extracellular matrix (ECM) components to the actin cytoskeleton and transmit chemical and mechanical signals into the cells through adhesion complexes. Integrin-activated downstream pathways have been implicated in the regulation of various cellular functions, including proliferation, survival, migration, and differentiation. Integrin-based attachment to the...

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PMID: 24677721
DOI: 10.1002/bdrc.21059

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