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Article

Integrin alpha8beta1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesis.

Cell - 7 Mar 1997

Müller U, Wang D, Denda S, Meneses J J, Pedersen R A, Reichardt L F

Abstract excerpt

We present genetic evidence that integrins regulate epithelial-mesenchymal interactions during organogenesis. Mice with a mutation in the alpha8 gene do not express the integrin alpha8 beta1 and exhibit profound deficits in kidney morphogenesis. In wild-type animals, inductive interactions betwee...

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Identifiers

PMID: 9054500
DOI: 10.1016/s0092-8674(00)81903-0
PMCID: PMC2711892

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9054500-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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