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Integrin Signaling in the Central Nervous System in Animals and Human Brain Diseases

27 Jan 2022

Abstract excerpt

The integrin family is involved in various biological functions, including cell proliferation, differentiation and migration, and also in the pathogenesis of disease. Integrins are multifunctional receptors that exist as heterodimers composed of α and β subunits and bind to various ligands, including extracellular matrix (ECM) proteins; they are found in many animals, not only vertebrates (e.g., mouse, rat, and...

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PMID: 35163359
DOI: 10.3390/ijms23031435

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