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Article

The role of integrins in inflammation and angiogenesis

7 Oct 2020

Abstract excerpt

Integrins are heterodimeric transmembrane cell adhesion molecules made up of alpha (α) and beta (β) subunits arranged in numerous dimeric pairings. These complexes have varying affinities to extracellular ligands. Integrins regulate cellular growth, proliferation, migration, signaling, and cytokine activation and release and thereby play important roles in cell proliferation and migration, apoptosis, tissue...

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PMID: 33027803
DOI: 10.1038/s41390-020-01177-9

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