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Article

Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis.

Genes & development - 1 Oct 2003

Aszodi Attila, Hunziker Ernst B, Brakebusch Cord, Fässler Reinhard

Abstract excerpt

Beta1 integrins are highly expressed on chondrocytes, where they mediate adhesion to cartilage matrix proteins. To assess the functions of beta1 integrin during skeletogenesis, we inactivated the beta1 integrin gene in chondrocytes. We show here that these mutant mice develop a chondrodysplasia o...

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Identifiers

PMID: 14522949
DOI: 10.1101/gad.277003
PMCID: PMC218082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14522949-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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