Article
Swi5 acts in meiotic DNA joint molecule formation in Schizosaccharomyces pombe.
Genetics - 1 Dec 2004
Ellermeier Chad, Schmidt Henning, Smith Gerald R
Abstract excerpt
Previously isolated Schizosaccharomyces pombe swi5 mutants are defective in mitotic mating-type switching and in repair of meiotic recombination-related DNA double-strand breaks. Here, we identify the swi5 gene, which encodes an 85-amino-acid polypeptide, similar to Sae3 of Saccharomyces cerevisiae, with an N-terminal predicted coiled-coil domain. A swi5 complete deletion mutant had normal mitotic growth rate but...
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