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Article

A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe.

Nucleic acids research - 1 Jan 2004

Bjerling Pernilla, Ekwall Karl, Egel Richard, Thon Geneviève

Abstract excerpt

The mating-type region of the fission yeast Schizosaccharomyces pombe comprises three loci: mat1, mat2-P and mat3-M. mat1 is expressed and determines the mating type of the cell. mat2-P and mat3-M are two storage cassettes located in a 17 kb heterochromatic region with features identical to those of mammalian heterochromatin. Mutations in the swi6+, clr1+, clr2+, clr3+, clr4+ and clr6+ genes were obtained in...

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Identifiers

PMID: 15317867
DOI: 10.1093/nar/gkh780
PMCID: PMC516054

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Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe.PMID 15317867Read ↗

Silencing motifs in the Clr2 protein from fission yeast, Schizosaccharomyces pombe.Semantic proximity Read ↗

Three additional linkage groups that repress transcription and meiotic recombination in the mating-type region of Schizosaccharomyces pombe.Semantic proximity Read ↗

Localization and properties of a silencing element near the mat3-M mating-type cassette of Schizosaccharomyces pombe.Semantic proximity Read ↗

H3K9me-independent gene silencing in fission yeast heterochromatin by Clr5 and histone deacetylases.Semantic proximity Read ↗

Histone deacetylase homologs regulate epigenetic inheritance of transcriptional silencing and chromosome segregation in fission yeast.Semantic proximity Read ↗

Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complexSemantic proximity Read ↗

Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity.Semantic proximity Read ↗

Schizosaccharomyces pombe mst2+ encodes a MYST family histone acetyltransferase that negatively regulates telomere silencing.Semantic proximity Read ↗

The clr1 locus regulates the expression of the cryptic mating-type loci of fission yeast.Semantic proximity Read ↗

CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing.Semantic proximity Read ↗

Identification of Uhp1, a ubiquitinated histone-like protein, as a target/mediator of Rhp6 in mating-type silencing in fission yeast.Semantic proximity Read ↗

Solution structure, domain features, and structural implications of mutants of the chromo domain from the fission yeast histone methyltransferase Clr4.Semantic proximity Read ↗

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