Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction.

Journal of medical genetics - 1 Oct 2004

Cornelis M C, El-Sohemy A, Campos H

Abstract excerpt

BACKGROUND: There is growing evidence that DNA damage caused by mutagens found in tobacco smoke may contribute to the development of coronary heart disease (CHD). In order to bind to DNA many mutagens require metabolic activation by cytochrome P450 (CYP) 1A1 or CYP1A2. The objective of this study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Costa Rica
Share to Cytochrome P-450 CYP1A1
Share to Cytochrome P-450 CYP1A2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Myocardial Infarction

Share to Polymorphism, Genetic

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 15466009
DOI: 10.1136/jmg.2004.022012
PMCID: PMC1735605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15466009-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction.PMID 15466009Read ↗

Coffee, CYP1A2 genotype, and risk of myocardial infarction.Semantic proximity Read ↗

Microsomal epoxide hydrolase genotype and risk of myocardial infarction.Semantic proximity Read ↗

Polymorphisms of cytochrome P450 1A1, cigarette smoking and risk of coronary artery disease.Semantic proximity Read ↗

Association of CYP2C8, CYP2C9 and CYP2J2 gene polymorphisms with myocardial infarction in South Indian population.Semantic proximity Read ↗

The CYP2J2 G-50T polymorphism and myocardial infarction in patients with cardiovascular risk profile.Semantic proximity Read ↗

Impact of smoking, smoking cessation, and genetic polymorphisms on CYP1A2 activity and inducibility.Semantic proximity Read ↗

Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction.Semantic proximity Read ↗

Genetic variance in CYP2C8 and increased risk of myocardial infarction.Semantic proximity Read ↗

GSTM1, GSTT1 and CYP1A1 detoxification gene polymorphisms and susceptibility to smoking-related coronary artery disease: a case-only study.Semantic proximity Read ↗

Glutathione S-transferase M1 null genotype is associated with a decreased risk of myocardial infarction.Semantic proximity Read ↗

CYP1B1 genotype and risk of cardiovascular disease, pulmonary disease, and cancer in 50,000 individuals.Semantic proximity Read ↗

Associations between polymorphisms in the AHR and CYP1A1-CYP1A2 gene regions and habitual caffeine consumption.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.