Article
Associations between polymorphisms in the AHR and CYP1A1-CYP1A2 gene regions and habitual caffeine consumption.
The American journal of clinical nutrition - 1 Sept 2012
Josse Andrea R, Da Costa Laura A, Campos Hannia, El-Sohemy Ahmed
Abstract excerpt
BACKGROUND: Recent genome-wide association studies (GWASs) from populations of European descent identified single nucleotide polymorphisms (SNPs) in aryl-hydrocarbon receptor (AHR) and cytochrome P450 1A1 and 1A2 (CYP1A1-CYP1A2) genes that are associated with habitual caffeine and coffee consumption. OBJECTIVE: We examined whether these SNPs (AHR: rs6968865 and rs4410790; CYP1A1-CYP1A2: rs2472297 and rs2470893)...
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