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Article

Polymorphisms of cytochrome P450 1A1, cigarette smoking and risk of coronary artery disease.

Mutation research - 10 Jul 2009

Yeh Chih-Ching, Sung Fung-Chang, Kuo Li-Tang, Hsu Wan-Ping, Chu Hsiang-Yu

Abstract excerpt

Epidemiological evidence has demonstrated a strong relationship between cigarette smoking and coronary artery disease (CAD). Cytochrome P450 1A1 (CYP1A1) is a key enzyme that metabolizes the cigarette toxin relevant to smoking-induced atherogenesis. This case-control study examined the role of CYP1A1 polymorphisms, CYP1A1 2A (T6235C) and CYP1A1 2C (A4889G), in susceptibility to smoking-related CAD. We recruited...

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Source

Identifiers

PMID: 19563927
DOI: 10.1016/j.mrfmmm.2009.04.001

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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