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Article

Altered terminal glycosylation and the pathophysiology of CF lung disease.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Aug 2004

Rhim Andrew D, Stoykova Lidia I, Trindade Arvind J, Glick Mary Catherine, Scanlin Thomas F

Abstract excerpt

Altered terminal glycosylation, with increased fucosylation and decreased sialylation, is a hallmark of the cystic fibrosis (CF) glycosylation phenotype. The glycosylation phenotype of CF airway epithelial cells has been modulated by the expression of wtCFTR. Understanding the effects of mutant CFTR on glycosylation may provide further insight into the regulation of glycoconjugate processing as well as new...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15463936
DOI: 10.1016/j.jcf.2004.05.021

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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