Article
Terminal glycosylation in cystic fibrosis (CF): a review emphasizing the airway epithelial cell.
Glycoconjugate journal - 1 Sept 2001
Rhim A D, Stoykova L, Glick M C, Scanlin T F
Abstract excerpt
Altered terminal glycosylation, with increased fucosylation and decreased sialylation is a hallmark of the cystic fibrosis (CF) glycosylation phenotype. Oligosaccharides purified from the surface membrane glycoconjugates of CF airway epithelial cells have the Lewis x, selectin ligand in terminal positions. This review is focused on the investigations of the glycoconjugates of the CF airway epithelial cell...
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