Article
Terminal glycosylation in cystic fibrosis.
Biochimica et biophysica acta - 8 Oct 1999
Scanlin T F, Glick M C
Abstract excerpt
Cystic fibrosis (CF) is a common genetic disease for which the gene was identified within the last decade. Pulmonary disease predominates in this ultimately fatal disease and current therapy only slows the progression. CF transmembrane regulator (CFTR), the gene product, is an integral membrane glycoprotein that normally functions as a chloride channel in epithelial cells. The most common mutation, deltaF508,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
