Article
Cystic fibrosis and bacterial colonization define the sputum N-glycosylation phenotype.
Glycobiology - 1 Jan 2015
Venkatakrishnan Vignesh, Thaysen-Andersen Morten, Chen Sharon C A, Nevalainen Helena, Packer Nicolle H
Abstract excerpt
Although mucin O-glycosylation of sputum from individuals suffering from cystic fibrosis (CF) is known to be altered relative to their unaffected counterparts, protein N-glycosylation of CF sputum remains structurally and functionally under-characterized. We report the first N-glycome of soluble proteins in sputum derived from five CF patients, two pathogen-free and two pathogen-infected/colonized non-CF...
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