Article
The evolutionarily conserved gene LNP-1 is required for synaptic vesicle trafficking and synaptic transmission.
The European journal of neuroscience - 1 Feb 2008
Ghila Luiza, Gomez Marie
Abstract excerpt
The control of vesicle-mediated transport in nerve cells is of great importance in the function, development and maintenance of synapse. In this paper, we characterize the new Caenorhabditis elegans gene, lnp-1. The lnp-1 gene is broadly distributed in many neuronal structures and its localization is dependent of the UNC-104/kinesin protein. Deletion mutations in lnp-1 result in increased resistance to aldicarb,...
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