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Article

The endo-lysosomal sorting machinery interacts with the intermediate filament cytoskeleton.

Molecular biology of the cell - 1 Dec 2004

Styers Melanie L, Salazar Gloria, Love Rachal, Peden Andrew A, Kowalczyk Andrew P, Faundez Victor

Abstract excerpt

Cytoskeletal networks control organelle subcellular distribution and function. Herein, we describe a previously unsuspected association between intermediate filament proteins and the adaptor complex AP-3. AP-3 and intermediate filament proteins cosedimented and coimmunoprecipitated as a complex free of microtubule and actin binding proteins. Genetic perturbation of the intermediate filament cytoskeleton triggered...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15456899
DOI: 10.1091/mbc.e04-03-0272
PMCID: PMC532017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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