Article
PHR1, a PH domain-containing protein expressed in primary sensory neurons.
Molecular and cellular biology - 1 Oct 2004
Xu Shunbin, Wang Yanshu, Zhao Haiqing, Zhang Lilei, Xiong Weihong, Yau King-Wai, Hiel Hakim, Glowatzki Elisabeth, Ryugo David K, Valle David
Abstract excerpt
Previously, we identified PHR1 as an abundantly expressed gene in photoreceptors and showed that it encodes four isoforms, each with N-terminal pleckstrin homology (PH) and C-terminal transmembrane domains. To better understand PHR1 function and expression, we made a Phr1 null mouse by inserting a beta-galactosidase/neor cassette into exon 3. In addition to photoreceptors, we found abundant expression of specific...
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